Anaesthesia Notes

Catalogued as “Clearance” until 8 September 2026, when it was renamed. Pharmacology uses that word for drug clearance and the order of kinetics; both questions here are renal, and one registry keyed on the bare string sent them to the pharmacokinetics page.

Written questions

Model answers available

Physiology3 + 3 + 4 marks

Physiology SAQ Paper 1

A patient who has undergone major abdominal surgery develops oliguria.
(a)Define GFR and state its principal determinants.3 marks
(b)Describe the physiological mechanisms regulating renal blood flow and GFR.3 marks
(c)Explain how ADH and RAAS conserve sodium and water during hypovolaemia.4 marks

Model answer available

Catalogued

Questions without a written answer yet

2018Physiology5 + 5 marks

(a)Describe the use of renal clearance to estimate the glomerular filtration rate5
(b)Justify the use of renal clearance of various substances for the above estimation5

Answer not yet written

2001Physiology

What is renal clearance?
Using this concept, describe in detail how glomerular filtration be determined

Answer not yet written

Single best answer

5 SBAs on renal physiology

Physiology SBA Paper 15

Practise all 5

Viva

2 viva questions

Why can NSAIDs precipitate renal dysfunction in hypovolaemia?
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They inhibit vasodilator prostaglandins, removing afferent-arteriolar protection.
Physiology SAQ Paper 1 · Q4 →
What can very high angiotensin II do?
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Constriction of both arterioles plus mesangial contraction may reduce RBF, Kf and GFR.
Physiology SAQ Paper 1 · Q4 →

Renal physiology questions,clearance, filtration and the concepts behind them.

Renal physiology questions,
clearance, filtration and the concepts behind them.